Magnesium Glycinate

Magnesium is the fourth most abundant mineral in the human body (behind calcium, potassium and sodium), and is essential for DNA and RNA synthesis, cellular repair, and maintaining antioxidant status of the cell. Simpill Supplements Magnesium Glycinate is one of the most readily absorbed forms of magnesium supplements available with the added benefit of less digestive side effects compared to other magnesium forms.

Researchers have found that up to 50% of the population is magnesium deficient. Known as the "invisible deficiency" due inaccuracies in measuring the body's magnesium stores via standard serum levels, magnesium intake from natural foods has decreased over the past few decades due to industrialized agriculture and population dietary changes. Low magnesium intake has been associated with the development of various disease states such as osteoporosis (weak bones), hypertension (high blood pressure), heart disease, stroke, metabolic syndrome (obesity), and diabetes.

Studied Benefits:

Osteoporosis (Weak Bones)

• Magnesium plays a key role in bone and muscle formation by assisting in the activation of vitamin D. Population research also suggests that increased magnesium intake is related to increased bone mineral density. Preliminary clinical research shows taking magnesium 300-1800mg orally for 6-18 months might reduce bone loss and bone turnover in postmenopausal patients with osteoporosis.

Hypertension (High Blood Pressure)

• In 2022, the US Food and Drug Administration (FDA) approved a qualified health claim stating that diets with adequate magnesium may reduce the risk of high blood pressure. Additionally, a recent meta-analyses showed that taking magnesium 120-1000mg daily can lower systolic blood pressure by 2-4 mmHg and diastolic blood pressure by 2 mmHg.

Diabetes

• Higher dietary magnesium intake is associated with lower fasting insulin concentrations and reduced risk of developing type 2 diabetes in adults and obese children. Additionally, population research in adults with type 2 diabetes also revealed that a dietary magnesium intake of less than 250mg daily is associated with a 56% higher risk of mortality.

Metabolic Syndrome

• Higher magnesium intake from diets and supplements is associated with a 27% lower risk of developing metabolic syndrome in healthy females, and a 31% lower risk in healthy young adults. Additional population research suggests that people with low serum magnesium levels are 6-7 times more likely to have metabolic syndrome than people with normal magnesium levels.

Migraine

• Small clinical studies in adults with migraine suggest that taking oral, high-dose magnesium citrate 600-1830mg daily in divided doses for up to 3 months seems to modestly reduce the frequency and severity of headaches when compared with baseline or placebo.

Anxiety, Depression, & Stress

• Further studies are needed to recommend true benefit. However, a 2017 randomized controlled trial of 112 participants demonstrated clinically significant improvements in mild-to-moderate depression, as well as improvements in anxiety scores evaluated from patient health assessments. Additionally, a slightly larger trial in 2021 found a clinically significant benefit in daily life for individuals with stress.

Suggested Use: As a dietary supplement, take one to three (1-3) capsules daily or as directed by your healthcare professional.

Additional Consideration: Vitamin D₃ metabolism requires adequate levels of magnesium, and supplement recommendations include taking both of these supplements daily. Consider taking Simpill Supplements Vitamin D₃ and Simpill Supplements Magnesium Glycinate for optimal benefit.

Dietary Considerations:

• 100% Natural & Vegetarian
• Non-GMO
• Gluten Free
• Allergen Free
• Lactose Free

Ingredients: Magnesium (from 2.500mg Magnesium Glycinate), Hypromellose (capsule), Magnesium Stearate, Silicon Dioxide, Rice Flour

Manufacturer Country: USA

Amount: 90 caps

Gross Weight: 0.25lb (113g)

Caution: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Warning: Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.

The Food and Drug Administration has not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease.